Invitrogen™ CD8 beta Monoclonal Antibody (3.4.1), PE

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
PIMA517592	Invitrogen™ MA517592	50 μg
PIMA517593	Invitrogen™ MA517593	200 μg

Description

CD8 beta Monoclonal Antibody for Flow

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Specifications

• Antigen: CD8 beta
• Concentration: 0.1 mg/mL
• Applications: Flow Cytometry
• Conjugate: PE
• Host Species: Mouse
• Regulatory Status: RUO
• Formulation: PBS with 4-5mg/mL BSA and 0.02% sodium azide
• Gene Accession No.: P05541
• Gene ID (Entrez): 24931
• Immunogen: Rat/mouse T cell hybrids expressing CD8.
• Product Type: Antibody

• Clone: 3.4.1
• Content And Storage: 4°C, do not freeze
• Classification: Monoclonal
• Form: Liquid
• Isotype: IgG1
• Target Species: Rat
• Gene: Cd8b
• Gene Alias: CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8a; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; CD8B1; CD8beta; CD8BP; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3
• Gene Symbols: Cd8b
• Primary or Secondary: Primary
• Purification Method: Protein G