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Invitrogen™ CD8 beta Monoclonal Antibody (CT-CD8b), APC
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Catalog No. PIMA517844
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100 μg
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Catalog No. Quantity
PIMA517844 100 μg
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Catalog No. PIMA517844 Supplier Invitrogen™ Supplier No. MA517844
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Description

Rat Monoclonal Antibody

MA5-17844 targets CD8b/LYT3 in FACS applications and shows reactivity with Mouse samples. The MA5-17844 immunogen is mouse CD8 β.

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD8 beta
Applications Flow Cytometry
Classification Monoclonal
Clone CT-CD8b
Concentration 0.1 mg/mL
Conjugate APC
Formulation PBS with 4-5mg/mL BSA and 0.02% sodium azide
Gene Cd8b1
Gene Accession No. P10300
Gene Alias CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta polypeptide precursor; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta; CD8 beta chain; CD8a; CD8alpha; CD8B; CD8b antigen; CD8b molecule; CD8b molecule pseudogene; CD8B1; CD8beta; CD8BP; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3
Gene Symbols Cd8b1
Host Species Rat
Immunogen Mouse CD8 β.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12526
Target Species Mouse
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG2a
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