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CD8 Mouse anti-Human, Clone: CA-8, Abnova™

Mouse monoclonal antibody raised against full length native of human CD8.

Manufacturer:  Abnova Corporation MAB12451

Catalog No. 89-933-871


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Description

Description

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq]

Specifications

Specifications

CD8
CA-8
Mouse monoclonal antibody raised against full length native of human CD8.
Lyophilized from ascites fluid (1.2% sodium acetate, 2mg BSA, 0.01mg sodium azide)
CD8/Leu2/MAL/p32
Mouse
IgG2a
RUO
Primary
925/926
Immunohistochemistry (Frozen)
Unconjugated
Immunohistochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
Lyophilized
CD8A
Native purified CD8 from human thymocytes.
100 ug
Store at −20°C. After reconstitution with 1mLof 1.2% sodium acetate or neutral PBS and concentration will be 100μg/mL, store at −20°C. Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
SDS
Documents
Product Certifications
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