CD8 Mouse anti-Human, PE-Cy7, Clone: RPA-T8, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 557746

Catalog No. BDB557746

Description

Clone RPA-T8 reacts with the α subunit (32kDa) of the two-chain complex expressed on T-cytoxic/suppressor cell populations. CD8 molecule binds to HLA class I molecules during interaction of CD8+ T cells with antigen-presenting cells or with target cells. RPA-T8 reacts with approximately 13-48% of peripheral blood lymphocytes and 80% of thymocytes, as well as a subset of NK cells. RPA-T8 and HIT8a (Mfr. No.555337) are not cross-blocking. This clone also reacts with a subset of peripheral blood lymphocytes, but not monocytes nor granulocytes, of baboon and both rhesus and cynomolgus macaque monkeys. In general, a higer frequency of CD8+ and CD4+CD8+ lymphocytes are observed in non-human primates compared to normal human donors. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only.

Host Species: Mouse
Clone: RPA-T8
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

Specifications

• Antigen: CD8
• Classification: Monoclonal
• Conjugate: PE-Cyanine7
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Immunogen: Human CD8a
• Quantity: 100 Tests
• Research Discipline: Immunology
• Target Species: Baboon, Cynomolgus, Human, Rhesus Monkey
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: RPA-T8
• Description: CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.