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  6. CD8 Mouse anti-Human, PE-Cy7, Clone: RPA-T8, BD

CD8 Mouse anti-Human, PE-Cy7, Clone: RPA-T8, BD

Catalog No. BDB557746 Shop All BD Biosciences Products
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Description

Mouse Monoclonal Antibody

Clone RPA-T8 reacts with the α subunit (32kDa) of the two-chain complex expressed on T-cytoxic/suppressor cell populations. CD8 molecule binds to HLA class I molecules during interaction of CD8+ T cells with antigen-presenting cells or with target cells. RPA-T8 reacts with approximately 13-48% of peripheral blood lymphocytes and 80% of thymocytes, as well as a subset of NK cells. RPA-T8 and HIT8a (Mfr. No.555337) are not cross-blocking. This clone also reacts with a subset of peripheral blood lymphocytes, but not monocytes nor granulocytes, of baboon and both rhesus and cynomolgus macaque monkeys. In general, a higer frequency of CD8+ and CD4+CD8+ lymphocytes are observed in non-human primates compared to normal human donors. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only.

Host Species: Mouse
Clone: RPA-T8
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD8
Applications Flow Cytometry
Classification Monoclonal
Clone RPA-T8
Conjugate PE-Cyanine7
Description CD8α; CD8A; CD8 alpha; Leu2; MAL; T8; p32
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human CD8a
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Baboon, Cynomolgus, Human, Rhesus Monkey
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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