Learn More
CD80 Mouse anti-Human, Clone: OTI2B11, lyophilized, TrueMAB™

Mouse Monoclonal Antibody
Supplier: OriGene CF501575

Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28, and of an inhibitory receptor CTLA-4 (CD152). Both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, and both molecules can also substitute for each other in this process. CD80 is rapidly induced on the surface of in vitro activated B cells, with Epstein Barr Virus (EBV) transformed B cell lines, with Burkitts lymphoma cell lines, with freshly isolated follicular B lymphoma cells, T cells, and monocytes. The B-lymphocyte activation antigen B7-1 provides regulatory signals for T lymphocytes as a consequence of binding to the CD28 and CTLA4 ligands of T cells. Diseases associated with CD80 dysfunction include gallbladder squamous cell carcinoma and myocarditis.Specifications
CD80 | |
Monoclonal | |
Unconjugated | |
CD80 | |
B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 | |
Mouse | |
Affinity Chromatography | |
RUO | |
941 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot | |
OTI2B11 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P33681 | |
CD80 | |
Full length human recombit protein of human CD80 produced in HEK293T cell. | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.