CD81 Mouse anti-Human, PE, Clone: JS-81, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 561957

Catalog No. BDB561957

Description

JS-81 identifies the newly clustered CD81 antigen, a 26 kDa, type III transmembrane protein (also known as TAPA-1) that is involved in cell growth and signal transduction. CD81 has a very broad cellular distribution, being expressed on cells of hematopoietic, neuroectodermal and mesenchymal origin. MAbs to CD81 have been shown to have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Immunoprecipitation studies reveal that CD81 is a component of a multimolecular complex which can include the Leu13 molecule, and the CD19 and CD21 molecules in B cells. MAbs to CD81 are reported to induce homotypic cell aggregation.

Specifications

• Antigen: CD81
• Classification: Monoclonal
• Conjugate: PE
• Formulation: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Canine, Human, Rabbit
• Isotype: IgG1 κ

• Applications: Flow Cytometry
• Clone: JS-81
• Description: TAPA-1
• Host Species: Mouse
• Quantity: 25 Tests
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.