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Invitrogen™ CD82 Polyclonal Antibody
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Catalog No. PIPA583042
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100 μL
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PIPA583042 100 μL
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Catalog No. PIPA583042 Supplier Invitrogen™ Supplier No. PA583042
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Rabbit Polyclonal Antibody

Immunogen sequence: NMGKLKQEMG GIVTELIRDY NSSREDSLQD AWDYVQAQVK CCGWVSFYNW TDNAELMNRP EVTYPCSCEV KGEEDNSLSV RKGFCEAPGN RTQSGNHPED WPVYQEGC Highest antigen sequence indentity to the following orthologs: Rat - 60%, Mouse - 63%.

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD82
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.1 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CD82
Gene Accession No. P27701
Gene Alias 4F9; AA682076; AL023070; C33; C33 antigen; Cd82; CD82 antigen; CD82 antigen (R2 leukocyte antigen antigen detected by monoclonal and antibody IA4)); CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); CD82 molecule; GR15; IA4; Inducible membrane protein R2; KAI1; Kangai 1 (suppression of tumerigenicity 6 prostate) CD82 antigen; kangai 1 (suppression of tumorigenicity 6), prostate; kangai 1 (suppression of tumorigenicity 6, prostate); Kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1; Metastasis suppressor Kangai-1 homolog; R2; SAR2; ST6; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan27; tspan-27
Gene Symbols CD82
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human CD82. Recombinant protein control fragment (Product #RP-102387).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3732
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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