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CD86 (B7-2) Monoclonal Antibody (GL1), Brilliant Ultra Violet™ 395, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Specifications

Antigen CD86 (B7-2)
Clone GL1
Concentration 0.2 mg/mL
Applications Flow Cytometry
Classification Monoclonal
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
36-308-6280
Encompass
View Documents
LIFE TECHNOLOGIES
363086280
25 μg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
36-308-6282
Encompass
View Documents
LIFE TECHNOLOGIES
363086282
100 μg This item has been discontinued and is no longer available. Please call customer service for assistance: 1-800-766-7000. N/A
Description

Description

The GL1 mAb reacts with mouse CD86, an ∽80 kDa surface receptor also known as B7-2. CD86 and CD80 are members of the B7 family of costimulatory molecules. CD86 is expressed at low level on B cells, macrophages, and dendritic cells and is upregulated on B cells through a variety of surface stimuli including the BCR complex, CD40 and some cytokine receptors. CD86 is also expressed by activated mouse T cells and thioglycolate-elicited peritoneal cells. In addition to CD80 (B7-1), CD86 is a counter-receptor for the T cell surface molecules CD28 and CD152 (CTLA-4). This interaction plays a critical role in T-B crosstalk, T cell costimulation, autoantibody production and Th2-mediated Ig production. The kinetics of upregulation of CD86 upon stimulation, supports its major contribution during the primary phase of an immune response. Applications Reported: This GL1 antibody has been reported for use in flow cytometric analysis. Applications Tested: This GL1 antibody has been tested by flow cytometric analysis of stimulated mouse splenocytes. BUV395 is a dye that emits at 395nm and is intended for use on cytometers equipped with an Ultraviolet (355nm) laser. Excitation: 350nm; Emission: 395nm; Laser: Ultraviolet Laser.

CD86 (B7-2) Monoclonal antibody specifically detects CD86 (B7-2) in Mouse samples. It is validated for Flow Cytometry
Specifications

Specifications

CD86 (B7-2)
0.2 mg/mL
Monoclonal
Liquid
RUO
PBS with BSA and 0.09% sodium azide; pH 7.2
activation B7-2 antigen; B lymphocyte activation antigen B72; B7; B7.2; B70; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; Cd28l2; CD28LG2; CD86; CD86 antigen; CD86 antigen (CD28 antigen ligand 2, B7-2 antigen); CD86 antigen precursor; CD86 molecule; CLS1; CTLA-4 counter-receptor B7.2; early T cell costimulatory molecule-1; early T-cell costimulatory molecule 1; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly58; Ly-58; MB7; MB7-2; membrane glycoprotein; MGC34413; T-lymphocyte activation antigen CD86; TS/A-2
IgG2a κ
Affinity chromatography
Antibody
GL1
Flow Cytometry
Brilliant Ultraviolet 395
Rat
Mouse
P42082
12524
Primary
4° C, store in dark, DO NOT FREEZE!
CD86
SDS
Product Certifications
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