CD86 Mouse anti-Human, Clone: C86/1146, Abnova™

Catalog No.	Quantity
89-933-874	100 μg

Catalog No. 89-933-874 Supplier Abnova Corporation Supplier No. MAB13462

Description

Mouse monoclonal antibody raised against full length recombinant human CD86.

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq]

Specifications

• Antigen: CD86
• Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: C86/1146
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against full length recombinant human CD86.
• Dilution: Flow Cytometry (0.5-1 ug/10⁶ cells in 0.1 mL) Immunofluorescence (0.5-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (2-4 ug/mL) Western Blot (0.5-1 ug/mL) The optimal working dilution should be determ
• Formulation: In 10mM PBS.
• Gene Alias: B7-2/B70/CD28LG2/LAB72/MGC34413
• Gene Symbols: CD86
• Host Species: Mouse
• Immunogen: Recombinant protein corresponding to full length human CD86.
• Purification Method: Protein A/G purification
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 942
• Target Species: Human
• Content And Storage: Store at -20 to -80°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG1 κ