CD86 Mouse anti-Human, FITC, Clone: K86, Abnova™

Mouse monoclonal antibody raised against human CD86.

Supplier:  Abnova Corporation MAB12416

Catalog No. 89-933-875

Description

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq]

Specifications

• Antigen: CD86
• Classification: Monoclonal
• Conjugate: FITC
• Dilution: Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
• Gene Alias: B7-2/B70/CD28LG2/LAB72/MGC34413
• Host Species: Mouse
• Purification Method: Protein A/G affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 942
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1

• Applications: Flow Cytometry, Immunofluorescence
• Clone: K86
• Description: Mouse monoclonal antibody raised against human CD86.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
• Gene Symbols: CD86
• Immunogen: CD86
• Quantity: 50 Reactions
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid