CD86 Mouse anti-Rat, FITC, Clone: 24F, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555018

Catalog No. BDB555018

Description

The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24FmAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Flow Cytometry

Specifications

• Antigen: CD86
• Classification: Monoclonal
• Concentration: 0.5mg/mL
• Description: B7-2
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Applications: Flow Cytometry
• Clone: 24F
• Conjugate: FITC
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Immunogen: HTLV-1-transformed rat T-cell line Lewis-S1
• Quantity: 0.5 mg
• Research Discipline: Immunology
• Target Species: Rat
• Isotype: IgG1 κ

For Research Use Only.