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CD86 Mouse anti-Rat, FITC, Clone: 24F, BD

Catalog No. BDB555018 Shop All BD Biosciences Products
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50 μg
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BDB555018 0.5 mg
BDB561961 50 μg
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Catalog No. BDB555018 Supplier BD Biosciences Supplier No. 555018
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Description

Mouse Monoclonal Antibody

The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24FmAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Flow Cytometry

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD86
Applications Flow Cytometry
Classification Monoclonal
Clone 24F
Concentration 0.5mg/mL
Conjugate FITC
Description B7-2
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Immunogen HTLV-1-transformed rat T-cell line Lewis-S1
Purification Method Affinity Purified
Quantity 0.5 mg
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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