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CD86 Mouse anti-Rat, FITC, Clone: 24F, BD

Catalog No. BDB561961 Shop All BD Biosciences Products
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0.5 mg
50 μg
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BDB561961 50 μg
BDB555018 0.5 mg
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Catalog No. BDB561961 Supplier BD Biosciences Supplier No. 561961
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Description

Mouse Monoclonal Antibody

The 24F antibody reacts with CD86 (B7-2), a member of the Ig superfamily of transmembrane proteins. CD86, a ligand for CD28 and CD152 (CTLA-4), is one of the accessory molecules that plays an important role in T cell-B cell costimulatory interactions. CD86 is predominantly expressed on antigen-presenting cells. It can be upregulated on splenic B cells by in vitro polyclonal activation, such as LPS treatment. 24F mAb is reported to block the costimulatory function of rat CD86 and to immunoprecipitate CD86 from Lewis-S1 cell lysates.HTLV-1-transformed rat T-cell line Lewis-S1

This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD86
Applications Flow Cytometry
Classification Monoclonal
Clone 24F
Concentration 0.5mg/mL
Conjugate FITC
Description B7-2
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species Mouse
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Rat
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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