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CD89 Monoclonal Antibody (MIP8a), PE, Invitrogen™
Mouse Monoclonal Antibody
Specifications
Antigen | CD89 |
---|---|
Clone | MIP8a |
Applications | Flow Cytometry |
Classification | Monoclonal |
Conjugate | PE |
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
PIMA528108
|
Thermo Scientific
MA528108 |
25 Tests | N/A | N/A | N/A | ||||
Description
This antibody recognizes the human CD89 cell surface antigen, a 50-75 kDa cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R). CD89 is expressed by peripheral blood monocytes and neutrophils. MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes. Reconstitute with 1 mL distilled water.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.Specifications
CD89 | |
Flow Cytometry | |
PE | |
Mouse | |
Human | |
2204 | |
Primary | |
Antibody |
MIP8a | |
Monoclonal | |
Lyophilized | |
RUO | |
P24071 | |
IgG1 | |
4° C, store in dark, DO NOT FREEZE! |
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