CD89 Mouse anti-Human, Brilliant Violet 786, Clone: A59, BD Optibuild™

Catalog No.	Quantity
BDB744379	50 μg

Catalog No. BDB744379 Supplier BD Biosciences Supplier No. 744379

Description

Mouse Monoclonal Antibody

The A59 monoclonal antibody specifically recognizes CD89. CD89 is the Fc receptor for IgA (Fc α R), a 55-75 kDa glycoprotein expressed exclusively on cells of granulocytic and monocyte/macrophage lineages in peripheral blood, but not on lymphocytes. It is also expressed on promyelocytes in bone marrow and in the cytoplasm of fixed monocytes. This mAb does not block IgA binding and is more efficient than native IgA ligands in the isolation of Fc α R molecules. Fc α R plays a role in triggering phagocytosis and respiratory burst.

The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm. BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter). BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm. BV786 offers a bright choice for the 6th detector off the violet laser.

Specifications

• Antigen: CD89
• Classification: Monoclonal
• Clone: A59
• Concentration: 0.2mg/mL
• Conjugate: Brilliant Violet 786
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Gene Alias: FCAR, IgA Fc receptor, FcαR, FcalphaRI, CTB-61M7.2
• Host Species: Mouse
• Immunogen: Purified Human FcαR
• Purification Method: Affinity Purified
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
• Isotype: IgG1 κ