Invitrogen™ CD89 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5143971

Catalog No. PIPA5143971

Description

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human HL-60 whole cell, human U-937 whole cell, human Jurkat whole cell. ICC/IF: Hela cell. Flow: Hela cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Specifications

• Antigen: CD89
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Fcar
• Gene Alias: CD89; CTB-61M7.2; Fc alpha receptor; Fc fragment of IgA receptor; Fc fragment of IgA, receptor for; FcalphaRI; FCAR; IgA Fc receptor; immunoglobulin A Fc receptor; immunoglobulin A Fc receptor transcript variant 1; immunoglobulin A Fc receptor transcript variant 3; immunoglobulin A Fc receptor transcript variant 7; immunoglobulin A Fc receptor transcript variant 9; immunoglobulin A Fc receptor transcript variant deltaEC1; immunoglobulin A Fc receptor transcript variant deltaEC1 delta TM/C; immunoglobulin alpha Fc receptor
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2204
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 4mg trehalose and no preservative
• Gene Accession No.: P24071
• Gene Symbols: Fcar
• Immunogen: E.coli-derived human CD89/FCAR recombinant protein (Position: Q22-K287).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG