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CD8A Mouse anti-Human, APC, Clone: COV8, Abnova™

Catalog No. 89933882 Shop All Abnova Corporation Products
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89-933-882 50 Reactions
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Catalog No. 89-933-882 Supplier Abnova Corporation Supplier No. MAB12382
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Description

Mouse monoclonal antibody raised against human CD8A.

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

Antigen CD8A
Applications Flow Cytometry, Immunofluorescence
Classification Monoclonal
Clone COV8
Conjugate APC
Description Mouse monoclonal antibody raised against human CD8A.
Dilution Flow cytometry Immunofluorescence The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.4 (0.09% sodium azide, 0.2% BSA)
Gene Alias CD8/Leu2/MAL/p32
Gene Symbols CD8A
Host Species Mouse
Immunogen CD8A
Purification Method Protein A/G affinity chromatography
Quantity 50 Reactions
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 925
Target Species Human
Content And Storage Store at 4°C. Do not freeze.
Form Liquid
Isotype IgG1
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