CD8A Mouse anti-Human, Clone: COV8, Abnova™

Mouse monoclonal antibody raised against human CD8A.

Supplier:  Abnova Corporation MAB12378

Catalog No. 89-933-889

Description

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Specifications

• Antigen: CD8A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: Flow cytometry The optimal working dilution should be determined by the end user.
• Gene Alias: CD8/Leu2/MAL/p32
• Host Species: Mouse
• Purification Method: Protein A/G affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 925
• Content And Storage: Store at 4°C. Do not freeze.
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: COV8
• Description: Mouse monoclonal antibody raised against human CD8A.
• Formulation: In PBS, pH 7.4 (0.09% sodium azide)
• Gene Symbols: CD8A
• Immunogen: CD8A
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid