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CD8B Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501986219
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100 μL
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50-198-6219 100 μL
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Catalog No. 50-198-6219 Supplier Bioss Supplier No. BS4914R
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Rabbit Polyclonal Antibody

The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.

Specifications

Antigen CD8B
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Cd8b
Gene Accession No. P10966
Gene Alias BOS_11635; CD8; CD8 antigen 37 kDa chain; CD8 antigen beta polypeptide; CD8 antigen beta-chain; CD8 antigen, beta chain; CD8 antigen, beta chain 1; CD8 antigen, beta polypeptide 1 (p37); CD8 antigen, beta-chain; CD8 beta chain; CD8a; CD8alpha; Cd8b; CD8b antigen; CD8b molecule; Cd8b1; CD8beta; LEU2; Leu-2; LY3; Ly-3; Ly-C; Lymphocyte antigen 3; Lyt3; Lyt-3; MAL; OX-8 membrane antigen; p32; P37; T lymphocyte surface glycoprotein beta chain; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein CD8 beta chain; T-cell surface glycoprotein Lyt-3
Gene Symbols Cd8b
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human CD8B.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 926
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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