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CD9 Mouse, anti-Mouse, R718, Clone: KMC8, BD OptiBuild™

Catalog No. BDB751979 Shop All BD Biosciences Products
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Catalog No. BDB751979 Supplier BD Biosciences Supplier No. 751979
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Mouse Monoclonal Antibody

The KMC8 monoclonal antibody specifically binds to CD9 which is also known as Tetraspanin-29 (Tspan29). CD9 is a 24-kDa member of the transmembrane 4 superfamily, also called the tretraspanin family. In the mouse, CD9 is present on bone marrow myeloid cells, stromal cells, and megakaryocyte-committed progenitors| subsets of peripheral T and B lymphocytes| and neutrophils, platelets, dendritic cells, and bone marrow-derived macrophages. CD9 has been found to be associated with integrins and other cell-surface receptors. It appears to play roles in signal transduction and in regulating cellular adhesive properties. CD9 can also reportedly participate in T-cell costimulation and induction of apoptosis. The KMC8 antibody reportedly blocks certain CD9 functions and activates macrophages.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD9
Applications Flow Cytometry
Classification Monoclonal
Clone KMC8
Conjugate R718
Host Species Mouse
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Mouse
Content And Storage Refrigerate Upon Arrival
Form Liquid
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