CD90.1 Mouse, PE, Clone: OX-7, BD

Mouse Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
BDB551401	BD Biosciences 551401	0.1 mg
BDB554898	BD Biosciences 554898	0.2 mg

Description

CD90 (Thy-1) is a GPI-anchored membrane glycoprotein of the Ig superfamily which is involved in signal transduction. The OX-7 clone reacts with rat CD90 reported to be expressed by hematopoietic stem cells, early myeloid & erythroid cells, immature B lymphocytes in the bone marrow & peripheral lymphoid organs, thymocytes, recent thymic emigrants (a subset of CD45RC- peripheral T lymphocytes), neurons, glomerular mesangial cells, endothelium at inflammatory sites, mast cells, and dendritic cells. Rat dendritic epidermal T cells (DEC) have been
reported to be CD90 (Thy-1) negative, unlike those of the mouse. The OX-7 clone has been reported to crossreact with the mouse CD90.1 (Thy-1.1) alloantigen of the AKR/J and PL strains, but not CD90.2 (Thy-1.2) found on many mouse strains. In the mouse, CD90 is found on thymocytes, most peripheral T lymphocytes, some intraepithelial T lymphocytes (IEL, DEC), hematopoietic stem cells, and neurons, but not B lymphocytes. In addition, there is evidence that CD90 mediates adhesion of mouse thymocytes to mouse thymic stroma. The OX-7 clone has also been reported to crossreact with rabbit and guinea pig thymus, brain, and intestine. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: OX-7
Isotype: IgG1 κ
Species Reactivity: Mouse
Immunogen: Rat thymocyte Thy-1 antigen

Flow Cytometry

Specifications

• Antigen: CD90.1
• Concentration: 0.2mg/mL
• Classification: Monoclonal
• Host Species: Mouse
• Research Discipline: Immunology
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Isotype: IgG1 κ
• Purification Method: Affinity Purified
• Description: Rat Thy-1; Mouse Thy-1.1

• Clone: OX-7
• Applications: Flow Cytometry
• Conjugate: PE
• Regulatory Status: RUO
• Target Species: Guinea Pig, Mouse, Rabbit, Rat
• Immunogen: Rat thymocyte Thy-1 antigen
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

For Research Use Only.