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Invitrogen™ CD90 Monoclonal Antibody (T11D7e)
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Catalog No. MA181249
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250 μg
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MA181249 250 μg
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Catalog No. MA181249 Supplier Invitrogen™ Supplier No. MA181249
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Mouse Monoclonal Antibody

This antibody recognizes mouse and rat CD90, a monomorphic determinant in rat but polymorphic in mice. Clone T11D7e reacts with Thy1.1 mice (i.e. AKR and FVB mice), but not Thy1.2 mice such as CBA and BALB/c. Clone T11D7e is usefull for removal of T lymphocytes from cell populations by complement mediated cytotoxicity.

CD90 (Thy 1) antigen is a GPI linked glycoprotein member of the Immunoglobulin super family. CD90 is expressed in murine T cells, thymocytes, neural cells, Kupffer's cells and fibroblasts. CD90 may play a role in cell-cell or cell-ligand interactions during synaptogenesis and other events in the brain. CD90 can be used as a marker for a variety of stem cells and for the axonal processes of mature neurons. Structural study of CD90 led to the foundation of the Immunoglobulin superfamily, of which it is the smallest member, and led to the first biochemical description and characterization of a vertebrate GPI anchor. Diseases associated with CD90 dysfunction include nasopharyngeal carcinoma and thymoma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD90
Applications Cytotoxicity Assay, Flow Cytometry
Classification Monoclonal
Clone T11D7e
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide
Gene Thy1
Gene Accession No. P01830, P01831
Gene Alias CD7; CD90; CDw90; FLJ33325; membrane glycoprotein; T25; Thy 1.2; THY1; Thy-1; Thy-1 antigen; Thy-1 cell surface antigen; thy-1 glycoprotein; thy-1 membrane glycoprotein; Thy-1 protein; Thy-1 T-cell antigen; Thy1.1; Thy1.2; Thy-1.2; thymus cell antigen 1, theta; Thymus cell surface antigen
Gene Symbols Thy1
Host Species Mouse
Immunogen Xenogeneic rat thymocytes.
Purification Method Ammonium sulfate precipitation
Quantity 250 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21838, 24832
Target Species Mouse, Rat
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgM
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WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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