CD94 Mouse anti-Human, Brilliant Violet 510, Clone: HP-3D9, BD Optibuild™

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 743949

Catalog No. BDB743949

Description

The HP-3D9 monoclonal antibody specifically binds to a 70 kDa disulfide-linked dimer, also known as Kp43, expressed on natural killer (NK) cells, especially activated NK cells. It is also expressed onγ/δTCR+ T lymphocytes and on some CD8+CD56+α/βTCR+ clones. Reports demonstrate that HP-3D9 markedly inhibits cytolytic activity of polyclonally-activated NK cells. CD94 (Kp43) plays a role in regulation of the function of NK cell activation and adhesion

The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser. BV510 is a polymer-based dye that is brighter than BD Horizon V500. Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

Specifications

• Antigen: CD94
• Clone: HP-3D9
• Conjugate: Brilliant Violet 510
• Gene Alias: KLRD1, Killer cell lectin-like receptor subfamily D member 1, KP43
• Immunogen: Human NK Cells
• Quantity: 50 μg
• Primary or Secondary: Primary
• Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

• Classification: Monoclonal
• Concentration: 0.2mg/mL
• Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
• Host Species: Mouse
• Purification Method: Affinity Purified
• Regulatory Status: RUO
• Target Species: Human
• Isotype: IgG1 κ

Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov