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CD94 Mouse anti-Human, Brilliant Violet 711, Clone: HP-3D9, BD Optibuild™

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BDB743952 50 μg
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Catalog No. BDB743952 Supplier BD Biosciences Supplier No. 743952
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Description

Mouse Monoclonal Antibody

The HP-3D9 monoclonal antibody specifically binds to a 70 kDa disulfide-linked dimer, also known as Kp43, expressed on natural killer (NK) cells, especially activated NK cells. It is also expressed onγ/δTCR+ T lymphocytes and on some CD8+CD56+α/βTCR+ clones. Reports demonstrate that HP-3D9 markedly inhibits cytolytic activity of polyclonally-activated NK cells. CD94 (Kp43) plays a role in regulation of the function of NK cell activation and adhesion

The antibody was conjugated to BD Horizon™ BV711 which is part of the BD Horizon Brilliant™ Violet family of dyes. This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 711nm. BD Horizon BV711 can be excited by the violet laser and detected in a filter used to detect Cy™5.5 / Alexa Fluor™ 700-like dyes (eg, 712/20nm filter). Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors. However, the spillover can be corrected through compensation as with any other dye combination. BV711 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 711 nm. This dye offers a very bright choice for the violet laser. Due to the excitation and emission characteristics of the acceptor dye, there may be moderate spillover into the Alexa Fluor™ 700 and PerCP-Cy5.5 detectors. BV711 will also have moderate spillover into the BD Horizon Brilliant™ Violet 786 detector.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD94
Classification Monoclonal
Clone HP-3D9
Concentration 0.2mg/mL
Conjugate Brilliant Violet 711
Formulation Aqueous buffered solution containing ≤0.09% sodium azide.
Gene Alias KLRD1, Killer cell lectin-like receptor subfamily D member 1, KP43
Host Species Mouse
Immunogen Human NK Cells
Purification Method Affinity Purified
Quantity 50 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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Safety and Handling

WARNING: Reproductive Harm - www.P65Warnings.ca.gov
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