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CD95 Mouse anti-Human, FITC, Clone: DX2, BD

Mouse Monoclonal Antibody

Supplier:  BD Biosciences 555673

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Catalog No. BDB555673


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Description

Description

Reacts with the 45kDa transmembrane cell surface Fas or Apo-1 antigen (designated CD95 at the Fifth HLDA Workshop) which is expressed on a variety of normal and neoplastic cells. The Fas/Apo-1 antigen is a polypeptide, which plays a role in the programmed sequence of events leading to cell death, termed apoptosis. The DX2 clone specifically reacts with murine L cells, murine L1210 leukemia cells and murine P815 mastocytoma cells transfected with human Fas cDNA but not with untransfected parental cell lines. Cross-linking with DX2 delivers an apoptotic signal indicating that DX2 recognizes a functional epitope of the CD95 antigen. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.

Host Species: Mouse
Clone: DX2
Isotype: IgG1 κ
Species Reactivity: Human

Flow Cytometry

TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD95
Monoclonal
FITC
Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Human CD95-transfected L Cells
100 Tests
Immunology
Baboon, Canine, Cynomolgus, Human, Pig, Rhesus Monkey
IgG1 κ
Flow Cytometry
DX2
APO-1; FAS; TNFRSF6; APT1; ALPS1A; FAS1; FASTM; FASLG receptor
Mouse
Affinity Purified
RUO
Primary
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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