Invitrogen™ CD97 Monoclonal Antibody (MEM-180), APC

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA516825

Catalog No. PIMA516825

Description

Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4ºC in the dark. Once reconstituted, this product has a shelf life of approx. 18 months. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL.

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.

Specifications

• Antigen: CD97
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 1% BSA, 5% sucrose and 0.09% sodium azide
• Gene Accession No.: P48960
• Gene Symbols: ADGRE5, CD97
• Immunogen: CD97.
• Quantity: 100 Tests
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Flow Cytometry
• Clone: MEM-180
• Conjugate: APC
• Gene: ADGRE5
• Gene Alias: AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 976
• Content And Storage: 4°C, store in dark, DO NOT FREEZE!
• Form: Lyophilized

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov