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Invitrogen™ CD97 Polyclonal Antibody
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Catalog No. PIPA5110786
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100 μL
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PIPA5110786 100 μL
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Catalog No. PIPA5110786 Supplier Invitrogen™ Supplier No. PA5110786
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: RDSKTSSAEV TIQNVIKLVD ELMEAPGDVE ALAPPVRHLI ATQLLSNLED IMRILAKSLP KGPFTYISPS NTELTLMIQE RGDKNVTMGQ Highest antigen sequence indentity to the following orthologs: Rat - 51%, Mouse - 49%.

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD97
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.30 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene ADGRE5
Gene Accession No. P48960
Gene Alias AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Gene Symbols ADGRE5, CD97
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human CD97. Recombinant protein control fragment (Product #RP-90743).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 976
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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