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Invitrogen™ CD97 Polyclonal Antibody
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Catalog No. PIPA5120871
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100 μL
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PIPA5120871 100 μL
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Catalog No. PIPA5120871 Supplier Invitrogen™ Supplier No. PA5120871
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Rabbit Polyclonal Antibody

Positive test controls include: HepG2, Jurkat, Mouse lung, Rat liver. The target is usually found in the following locations: Cell membrane, Multi-pass membrane protein, Secreted, extracellular space. Immunogen sequence: NLEDIMRILA KSLPKGPFTY ISPSNTELTL MIQERGDKNV TMGQSSARMK LNWAVAAGAE DPGPAVAGIL SIQNMTTLLA NASLNLHSKK QAELEEIYES SIRGVQLRRL SAVNSIFLSH NNTKELNSPI LFAFSHLESS DGEAGRDPPA KDVMPGPRQE LLCAFWKSDS DRGGHWATEG CQVLGSKNGS TTCQCS.

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD97
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.82 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene ADGRE5
Gene Accession No. P48960, Q9Z0M6
Gene Alias AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Gene Symbols ADGRE5, CD97
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26364, 361383, 976
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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