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Invitrogen™ CD97 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5100714

Catalog No. PIPA5100714


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Description

Description

Antibody detects endogenous levels of total CD97.

CD97 is a G-protein-coupled seven-span transmembrane adhesive receptor that is constitutively expressed on granulocytes and monocytes and rapidly upregulated on T and B cells upon activation. CD97 is produced in alternatively spliced forms and its cellular ligand is CD55 (DAF), which protects various cell types from complement-mediated damage. Interaction of CD97 on leukocytes and CD55 on vessel cells probably facilitate leukocyte activation and migration into the tissues, similarly, CD97 seems to play a role in tumour migration and invasiveness. CD97 is involved in T cell regulation and peripheral granulocyte homeostasis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD97
Polyclonal
Unconjugated
ADGRE5
AA409984; Adgre5; adhesion G protein-coupled receptor E5; Cd97; CD97 antigen; CD97 antigen subunit alpha; CD97 antigen subunit beta; CD97 molecule; EGF-TM7 receptor; leukocyte antigen CD97; seven transmembrane helix receptor; seven-span transmembrane protein; seven-transmembrane, heterodimeric receptor associated with inflammation; TM7LN1
Rabbit
Affinity chromatography
RUO
26364, 361383, 976
-20°C
Liquid
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P48960, Q9Z0M6
ADGRE5, CD97
A synthesized peptide derived from human CD97(Accession P48960), corresponding to amino acid residues S451-D501.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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