Invitrogen™ CD98 Chimeric Recombinant Rabbit Monoclonal Antibody (RL388)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA548210

Catalog No. PIMA548210

Description

Specificity: This antibody recognises murine CD98, a heterodimeric cell surface glycoprotein.

CD98 (4F2) is a type II transmembrane glycoprotein which serves as the heavy chain of the heterodimeric amino acid transporters (HATs). CD98, linked to various light chains by disulfide bond, is responsible for cell surface expression and basolateral localization of this transporter complex in polarized epithelial cells and also interacts with beta1 integrins and increases their affinity for ligand. Besides its roles in amino acid transport, CD98 is thus involved in cell fusion and activation. It is implicated in regulation of cellular differentiation, growth and apoptosis.

Specifications

• Antigen: CD98 Chimeric
• Classification: Recombinant Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% ProClin 300
• Gene Accession No.: P10852
• Gene Symbols: SLC3A2
• Immunogen: This antibody was raised by immunising rats with an IL 2-producing subline of the mouse T lymphoma EL4.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG κ

• Applications: Flow Cytometry, Immunoprecipitation, T-Cell Activation, Western Blot, Immunocytochemistry
• Clone: RL388
• Conjugate: Unconjugated
• Gene: SLC3A2
• Gene Alias: 4F2; 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2hc; 4T2HC; AI314110; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; Cd98; CD98 antigen; CD98 heavy chain; CD98HC; Ly10; Ly-10; Ly-m10; Lymphocyte activation antigen 4F2 large subunit; MDU1; Mgp-2hc; monoclonal antibody 44D7; NACAE; RGD:3073}; SLC3A2; slc3a2 {ECO:0000312; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3 member 2; solute carrier family 3, member 2; type II transmembrane protein
• Host Species: Rabbit
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 17254
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid