CDC2/CDK1 Antibody (CDK1/873), Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2449150.2MG

Catalog No. NBP24491502

Description

Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

CDC2/CDK1 Monoclonal antibody specifically detects CDC2/CDK1 in Human, Monkey, Mink, Primate, S. pombe (Negative), Drosophila (Negative), Mouse (Negative), Rat (Negative), Xenopus (Negative), Yeast (Negative) samples. It is validated for Flow Cytometry, Immunohistochemistry-Paraffin, Immunofluorescence.

Specifications

• Antigen: CDC2/CDK1
• Classification: Monoclonal
• Concentration: 0.2 mg/mL
• Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 2 - 4 ug/ml, Immunofluorescence 1 - 2 ug/ml
• Gene Alias: CDC28A, CDC2MGC111195, cell cycle controller CDC2, Cell division control protein 2 homolog, Cell division protein kinase 1, cyclin-dependent kinase 1, DKFZp686L20222, EC 2.7.11.22, EC 2.7.11.23, G1 to S and G2 to M, p34 protein kinase, P34CDC2
• Host Species: Mouse
• Molecular Weight of Antigen: 34 kDa
• Quantity: 0.2 mg
• Research Discipline: Breast Cancer, Cancer, Cell Cycle and Replication, Core ESC Like Genes, Mitotic Regulators, Stem Cell Markers
• Gene ID (Entrez): 983
• Target Species: Human, Monkey, Mink, Primate, S. pombe (Negative), Drosophila (Negative), Mouse (Negative), Rat (Negative)
• Form: Purified

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
• Clone: CDK1/873
• Conjugate: Unconjugated
• Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
• Gene Symbols: CDK1
• Immunogen: Recombinant human CDK1 protein
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Test Specificity: Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1/ p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1/ p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
• Content And Storage: Store at 4C.
• Isotype: IgG2a κ

For Research Use Only