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Cdc20 Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501726152 Shop All Proteintech Group Inc Products
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50-172-6152 150 μL
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Catalog No. 50-172-6152 Supplier Proteintech Group Inc Supplier No. 102521AP150UL
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Description

Rabbit Polyclonal Antibody

Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation.

Specifications

Antigen Cdc20
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CDC20
Gene Accession No. Q12834
Gene Alias CDC20, CDC20A, p55CDC
Gene Symbols CDC20
Host Species Rabbit
Immunogen Cdc20 Fusion Protein Ag0295
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 991
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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