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Cdc25A Monoclonal Antibody (DCS-120), Invitrogen™

Catalog No. PIMA513794
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500 μL
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Catalog No. Quantity
PIMA513794 500 μL
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Catalog No. PIMA513794 Supplier Thermo Scientific Supplier No. MA513794

Description

Mouse Monoclonal Antibody

MA5-13794 targets CDC25A in IP, IHC (P) and WB applications and shows reactivity with Human and Rat samples. The MA5-13794 immunogen is purified recombinant CDC25A.

CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc25A
Applications Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DCS-120
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 15mM sodium azide; pH 7.4
Gene CDC25A
Gene Accession No. P30304, P48964, P48965
Gene Alias CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Gene Symbols CDC25A
Host Species Mouse
Immunogen Purified recombinant CDC25A
Purification Method Protein A
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12530, 171102, 993
Target Species Human, Mouse, Rat
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG2a
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