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CDC25A Polyclonal Antibody, Invitrogen™

Catalog No. PIPA5110699
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100 μL
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PIPA5110699 100 μL
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Catalog No. PIPA5110699 Supplier Thermo Scientific Supplier No. PA5110699

Description

Rabbit Polyclonal Antibody

Immunogen sequence: VAGKHQDLKY ISPEIMASVL NGKFANLIKE FVIIDCRYPY EYEGGHIKGA VNLHMEEEVE DFLLKKPIVP TDGKRVIVVF HCEFSSERGP RMCRYVRERD RLGNEYPKLH YPELYVLKGG YKEFFMKCQS Y

CDC25a is a member of the CDC25 family of phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. CDC25a is required for progression through G1 and S phases of the cell cycle. CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDC25A
Applications Immunocytochemistry, Immunofluorescence
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene CDC25A
Gene Accession No. P30304
Gene Alias CDC25A; CDC25A2; Cdc25m3; D9Ertd393e; Dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1
Gene Symbols CDC25A
Host Species Rabbit
Immunogen Recombinant Protein corresonding to Human CDC25A
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 993
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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