Invitrogen™ CDC25B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA587450

Catalog No. PIPA587450

Description

Immunogen sequence: MEVPQPEPAP GSALSPAGVC GGAQRPGHLP GLLLGSHGLL GSPVRAAASS PVTTLTQTMH DLAGLGSETP KSQVGTLLFR SRSRLTHLSL SRRASESSLS SESSESSDAG LCMDSPSPMD PHMAEQTFEQ AIQAASRIIR NEQFAIRRFQ SMPVRLLGHS PVLRNITNSQ APDGRRKSEA GSGAASSSGE DKENDGFVFK MPWKPTHPSS THALAEWASR REAFAQRPSS APDLMCLSPD RKMEVEELSP; Positive Samples: A-549; Cellular Location: Cytoplasm, centrosome, cytoskeleton, microtubule organizing center, spindle pole.

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Specifications

• Antigen: CDC25B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC25B
• Gene Alias: AI604853; CDC25B; CDC25HU2; Cdc25m2; cell division cycle 25B; dual specificity phosphatase Cdc25B; EC 3.1.3.48; M-phase inducer phosphatase 2; MPIP2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 994
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.93 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P30305
• Gene Symbols: CDC25B
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human CDC25B (NP_0686591).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG