Invitrogen™ Cdc25C Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA527790

Catalog No. PIPA527790

Description

Recommended positive controls: 293T, A431, Jurkat. Predicted reactivity: Chimpanzee (83%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

M-phase inducer phosphatase 3is an enzyme that in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Specifications

• Antigen: Cdc25C
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Cdc25c
• Gene Alias: CDC25; CDC25C; Cdc25m1; cell division cycle 25C; dual specificity phosphatase CDC25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 995
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.63 mg/mL
• Formulation: 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P30307
• Gene Symbols: Cdc25c
• Immunogen: Recombinant fragment corresponding to a region within amino acids 1 and 288 of Human CDC25C.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG