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Invitrogen™ Cdc25C Polyclonal Antibody
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Catalog No. PIPA588114
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100 μL
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PIPA588114 100 μL
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Catalog No. PIPA588114 Supplier Invitrogen™ Supplier No. PA588114
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PKLDKNPNLG EDQAEEISDE LMEFSLKDQE AKVSRSGLYR SPSMPENLNR PRLKQVEKFK DNTIPDKVKK KYFSGQGKLR KGLCLKKTVS LCDITITQML EEDSNQGHLI GDFSKVCALP TVSGKHQDLK YVNPETVAAL LSGKFQGLIE KFYVIDCRYP YEYLGGHIQG ALNLYSQEEL FNFFLKKPIV PLDTQKRIII VFHCEFSSER GPRMCRCLRE EDRSLNQYPA LYYPELYILK GGYRDFFPEY MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP; Positive Samples: K-562, HepG2, Raji, HeLa, SW480, Mouse eye, Mouse spleen, Mouse intestine; Cellular Location: Nucleus.

M-phase inducer phosphatase 3is an enzyme that in humans is encoded by theCDC25Cgene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc25C
Applications ELISA, Immunocytochemistry
Classification Polyclonal
Concentration 0.62 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cdc25c
Gene Accession No. P30307
Gene Alias CDC25; CDC25C; Cdc25m1; cell division cycle 25C; dual specificity phosphatase CDC25C; EC 3.1.3.48; mitosis inducer CDC25; M-phase inducer phosphatase 3; MPIP3; OTTHUMP00000159490; OTTHUMP00000224012; OTTHUMP00000224013; OTTHUMP00000224016; phosphotyrosine phosphatase; PPP1R60; protein phosphatase 1, regulatory subunit 60
Gene Symbols Cdc25c
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 174-473 of human CDC25C (NP_0017812).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 995
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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