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CDC27 Polyclonal Antibody, Bethyl Laboratories

Catalog No. 501559473
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50-155-9473 20 μL
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Catalog No. 50-155-9473 Supplier Bethyl Laboratories, Inc Supplier No. A301183AT
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat and Bovine

Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC3, also known as CDC27, a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), is a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. APC3 contains a tetratricopeptide repeat (TPR) region and interacts with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1.

Specifications

Antigen CDC27
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene CDC27
Gene Accession No. P30260
Gene Alias APC3, CDC27Hs, D0S1430E, D17S978E, HNUC
Gene Symbols CDC27
Host Species Rabbit
Immunogen Between 225 and 275
Purification Method Antigen affinity chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 996
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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