Invitrogen™ Cdc42EP2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536579

Catalog No. PIPA536579

Description

This antibody detects endogenous protein at a molecular weight of 23 kDa. Purity is >95% by SDS-PAGE.

Cdc42, a small GTPase, regulates Actin polymerization, elongation of cell shape and cell signaling through interactions with many different downstream effector proteins, most of which contain a Cdc42-binding motif known as a CRIB domain. Cdc42EP2 (Cdc42 effector protein 2), also known as BORG1 or CEP2, is a 210 amino acid intracytoplasmic protein that localizes to both the cytoplasm and the cytoskeleton and contains one CRIB domain. Highly expressed in heart and present at lower levels in liver and pancreas, Cdc42EP2 interacts with Cdc42 and is thought to be involved in the organization of the Actin cytoskeleton and may also influence Actin filament assembly and overall cell shape.

Specifications

• Antigen: Cdc42EP2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC42EP2
• Gene Alias: 1110008C05Rik; binder of Rho GTPases 1; Borg1; CDC42 effector protein (Rho GTPase binding) 2; CDC42 effector protein 2; CDC42EP2; CEP2; CRIB-containing BOGR1 protein; D19Bwg1013e
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 104252, 10435, 309175
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide; pH 7.2
• Gene Accession No.: O14613, Q5PQP4, Q8JZX9
• Gene Symbols: CDC42EP2
• Immunogen: Synthetic peptide corresponding to amino acids 1-50 of human Cdc42EP2.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG