Invitrogen™ Cdc42EP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA557102

Catalog No. PIPA557102

Description

Immunogen sequence: SLPTIGGSQA LMLPLLSPVT FNSKQESFGP AKLPRLSCEP VMEEKAQEKS SLLENGTVHQ GDTSW Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.

CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of, CDC42. This protein can interact with CDC42, as well as with the ras homolog gene family, member Q (ARHQ/TC10). Expression of this protein in fibroblasts has been shown to induce pseudopodia formation.

Specifications

• Antigen: Cdc42EP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC42EP3
• Gene Alias: 3200001F04Rik; AA986861; Binder of Rho GTPases 2; BORG2; CDC42 effector protein (Rho GTPase binding) 3; CDC42 effector protein 3; Cdc42ep3; CEP3; CRIB-containing BORG2 protein; MSE55-related Cdc42-binding protein; MSE55-related protein; UB1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10602
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9UKI2
• Gene Symbols: CDC42EP3
• Immunogen: Recombinant protein corresponding to Human Cdc42EP3. Recombinant protein control fragment (Product #RP-96179).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov