Invitrogen™ Cdc42EP5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5106637

Catalog No. PIPA5106637

Description

Antibody detects endogenous levels of total BORG3.

Cell division control protein 42 (CDC42), a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg (binder of Rho GTPases) family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to CDC42 and regulate its function negatively. The encoded protein may inhibit c-Jun N-terminal kinase (JNK) independently of CDC42 binding. The protein may also play a role in septin organization and inducing pseudopodia formation in fibroblasts [provided by RefSeq, Jul 2013].

Specifications

• Antigen: Cdc42EP5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CDC42EP5
• Gene Alias: 1700027J19Rik; 2010007O02Rik; binder of Rho GTPase 3; binder of Rho GTPases 3; BORG3; C85526; CDC42 effector protein (Rho GTPase binding) 5; CDC42 effector protein 5; CDC42EP5; Cep5; CRIB-containing BORG3 protein
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 148170, 58804
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q6NZY7, Q9Z0X0
• Gene Symbols: CDC42EP5
• Immunogen: A synthesized peptide derived from human CDC42EP5(Accession Q6NZY7), corresponding to amino acid residues M1-R38.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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