CDC45 Monoclonal Antibody (OTI8A1), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA811269

Catalog No. 50-168-3948

Description

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintece proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.

Specifications

• Antigen: CDC45
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: O75419
• Gene Symbols: CDC45
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-270 of human CDC45 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI8A1
• Conjugate: Unconjugated
• Gene: CDC45
• Gene Alias: CDC45L, CDC45L2, MGORS7, PORC-PI-1
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8318
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid