CDC45 Mouse anti-Human, Clone: OTI8A1, lyophilized, TrueMAB™

Catalog No.	Quantity
50-167-0564	100 μg

Catalog No. 50-167-0564 Supplier OriGene Supplier No. CF811269

Description

Mouse Monoclonal Antibody

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintece proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported.

Specifications

• Antigen: CDC45
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI8A1
• Conjugate: Unconjugated
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene: CDC45
• Gene Accession No.: O75419
• Gene Alias: CDC45L, CDC45L2, MGORS7, PORC-PI-1
• Gene Symbols: CDC45
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-270 of human CDC45 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 8318
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG1