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Invitrogen™ CDC45L Polyclonal Antibody
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Catalog No. PIPA579021
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100 μg
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Catalog No. Quantity
PIPA579021 100 μg
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Catalog No. PIPA579021 Supplier Invitrogen™ Supplier No. PA579021
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Description

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: rat testis tissue, rat thymus tissue, rat brain tissue, rat lung tissue, mouse testis tissue, mouse thymus tissue, mouse brain tissue, mouse lung tissue, mouse HEPA1-6 whole cell.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDC45L
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 500 μg/mL
Conjugate Unconjugated
Formulation PBS with 4mg trehalose and 0.05mg sodium azide
Gene Cdc45
Gene Accession No. O75419, Q9Z1X9
Gene Alias CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
Gene Symbols Cdc45
Host Species Rabbit
Immunogen E. coli-derived human CDC45L recombinant protein (Position: E166-A431).
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12544, 287961, 8318
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
Isotype IgG
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