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Invitrogen™ Cdc45L Polyclonal Antibody
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Catalog No. PIPA596047
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100 μL
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PIPA596047 100 μL
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Catalog No. PIPA596047 Supplier Invitrogen™ Supplier No. PA596047
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVVNVY NDTQIKLLIK QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVEQTMR RRQRREWEAR RRDILFDYEQ YEYHGTSSAM VMFELAWMLS KDLNDMLWWA IVGLTDQWVQ DKITQMKYVT DVGVLQRHVS RHNHRNEDEE NTLSVDCTRI; Positive Samples: U-251MG, HeLa, A-549, HL-60, HT-29, Mouse thymus; Cellular Location: Cytoplasm, Nucleus.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc45L
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Cdc45
Gene Accession No. O75419, Q9Z1X9
Gene Alias CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
Gene Symbols Cdc45
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CDC45 (NP_0034951).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12544, 287961, 8318
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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