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Invitrogen™ Cdc45L Recombinant Rabbit Monoclonal Antibody (JJ091-04)
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Catalog No. PIMA532474
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PIMA532474 100 μL
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Catalog No. PIMA532474 Supplier Invitrogen™ Supplier No. MA532474
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Description

Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenylation sites of this gene are reported.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc45L
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone JJ091-04
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene Cdc45
Gene Accession No. O75419, Q9Z1X9
Gene Alias CDC 45; CDC 45L; Cdc45; CDC45 cell division cycle 45 homolog; CDC45 like; CDC45L; CDC45L2; CDC45-related protein; Cell division control protein 45 homolog; cell division cycle 45; cell division cycle 45 homolog; cell division cycle 45-like 2; human CDC45; PORC PI 1; PORC-PI-1; UNQ374/PRO710
Gene Symbols Cdc45
Host Species Rabbit
Immunogen Synthetic protein within Human CDC45 aa 501-544.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12544, 287961, 8318
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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