CDC6 Mouse anti-Human, Clone: OTI1B3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF808439

Catalog No. 50-166-8856

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.

Specifications

• Antigen: CDC6
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: CDC6
• Gene Alias: CDC18L, HsCDC18, HsCDC6, MGORS5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 990
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Western Blot
• Clone: OTI1B3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q99741
• Gene Symbols: CDC6
• Immunogen: Full length human recombit protein of human CDC6 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1