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Invitrogen™ CDC6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA579022

Catalog No. PIPA579022


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Description

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, JURKAT whole cell, MM231 whole cell, HT1080 whole cell. IHC: rat testis tissue, human mammary cancer tissue.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CDC6
Polyclonal
Unconjugated
CDC6
CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
Rabbit
Antigen Affinity Chromatography
RUO
360621, 990
-20°C
Lyophilized
Immunohistochemistry (Paraffin), Western Blot
500 μg/mL
PBS with 5mg BSA and 0.05mg sodium azide
Q99741
CDC6
E.coli-derived human Cdc6 recombinant protein (Position: V147-A549).
100 μg
Primary
Human, Rat
Antibody
IgG
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