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CDC6 Rabbit anti-Human, Polyclonal , Abnova™

Catalog No. 89933906 Shop All Abnova Corporation Products
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89-933-906 100 μL
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Catalog No. 89-933-906 Supplier Abnova Corporation Supplier No. PAB29498
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CDC6 polyclonal antibody raised against recombinant human CDC6.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq]

Sequence: CQEEVSRPAGKDMMRKLEKHMTAEKGPMIVLVLDEMDQLDSKGQDVLYTLFEWPWLSNSHLVLIGIANTLDLTDRILPRLQAREKCKPQLLNFPP

Specifications

Antigen CDC6
Applications Immunofluorescence, Immunohistochemistry (PFA fixed)
Classification Polyclonal
Conjugate Unconjugated
Description CDC6 polyclonal antibody raised against recombinant human CDC6.
Dilution Immunofluorescence (1-4 ug/mL) Immunohistochemistry (1:10-1:20) The optimal working dilution should be determined by the end user.
Formulation In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide)
Gene Alias CDC18L/HsCDC18/HsCDC6
Gene Symbols CDC6
Host Species Rabbit
Immunogen Recombinant protein corresponding to amino acids of human CDC6.
Purification Method Antigen affinity purification
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 990
Target Species Human
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG
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