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Invitrogen™ CDC6 Recombinant Rabbit Monoclonal Antibody (JE59-52)
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Catalog No. FEMA550795
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FEMA550795 100 μL
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Catalog No. FEMA550795 Supplier Invitrogen™ Supplier No. MA550795
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Description

Rabbit Recombinant Monoclonal Antibody

Positive control: Hela cell lysate, HepG2 cell lysate, human striated muscle tissue, human testis muscle tissue. Predicted band size: 63 kDa Subcellular Location: Nucleus, Cytoplasm.

The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CDC6
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Recombinant Monoclonal
Clone JE59-52
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Gene CDC6
Gene Accession No. Q99741
Gene Alias CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6)
Gene Symbols CDC6
Host Species Rabbit
Immunogen Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 aa 41-90/560.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 990
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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