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Invitrogen™ CDC6 Recombinant Rabbit Monoclonal Antibody (JE59-52)
Rabbit Recombinant Monoclonal Antibody
Supplier: Invitrogen™ MA550795
Description
Positive control: Hela cell lysate, HepG2 cell lysate, human striated muscle tissue, human testis muscle tissue. Predicted band size: 63 kDa Subcellular Location: Nucleus, Cytoplasm.
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins.
Specifications
CDC6 | |
Recombinant Monoclonal | |
1 mg/mL | |
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4 | |
Q99741 | |
CDC6 | |
Synthetic phospho-peptide corresponding to residues surrounding Ser54 of Human Cdc6 aa 41-90/560. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG |
Immunohistochemistry (Paraffin), Western Blot | |
JE59-52 | |
Unconjugated | |
CDC6 | |
CDC18(S.pombe); CDC18L; cdc18-related protein; CDC6; CDC6 cell division cycle 6 homolog; CDC6-related protein; Cell division control protein 6 homolog; cell division cycle 6; cell division cycle 6 homolog; HsCDC18; HsCDC6; p62(cdc6) | |
Rabbit | |
Protein A | |
RUO | |
990 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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