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Cdc7 Monoclonal Antibody (DCS-341), Invitrogen™

Catalog No. PIMA512589
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500 μL
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Catalog No. Quantity
PIMA512589 500 μL
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Catalog No. PIMA512589 Supplier Thermo Scientific Supplier No. MA512589

Description

Mouse Monoclonal Antibody

MA5-12589 targets CDC7 Kinase in IHC (P), IP, and WB applications and shows reactivity with Human samples. The MA5-12589 immunogen is gST fusion protein full length CDC7.

CDC7 is a cell division cycle 7 homolog protein that is critical for the G1/S transition and is also essential for initiation of DNA replication as cell division occurs. CDC7 is expressed in many normal tissues, but the overexpression of CDC7 may be associated with neoplastic transformation for some tumors and transformed cell lines. CDC7/DBF4 kinase promotes S phase by alleviating an inhibitory activity in Mcm4 that evolved to integrate several protein kinase. CDC7 encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cdc7
Applications Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Clone DCS-341
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene CDC7
Gene Accession No. O00311
Gene Alias AI597260; Cdc7; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; Cdc7 Kinase; Cdc7l1; CDC7-like 1; CDC7-related kinase; cell division cycle 7; cell division cycle 7 (S. cerevisiae); cell division cycle 7 homolog; cell division cycle 7-like 1; cell division cycle 7-like protein 1; cell division cycle 7-related protein kinase; HsCDC7; Hsk1; huCDC7; MGC117361; MGC126237; MGC126238; MGC91067; muCdc7
Gene Symbols CDC7
Host Species Mouse
Immunogen GST fusion protein full length CDC7
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8317
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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